Yes, ketamine has been extensively researched, particularly in recent years, for its potential benefits in treating a range of mental health conditions. Its use is supported by a growing body of evidence from clinical trials and studies that have demonstrated its rapid antidepressant effects and its potential to help with conditions like PTSD and anxiety.

Ketamine was first synthesized in the 1960s and has long been used as an anesthetic in both human and veterinary medicine. Its safety profile and ability to provide anesthesia without significantly depressing respiration have made it a valuable tool in medical settings for the last 60 years.